IVF and Preconception Nutrition
Preconception nutrition + IVF
IVF outcomes are influenced by many factors — clinical protocol, age, underlying causes of infertility, and embryo quality. The research on preconception nutrition consistently points to a role in supporting baseline health during stimulation cycles and the wider preconception window.
What the research says
Several systematic reviews and meta-analyses have looked at specific nutrients and IVF outcomes. Notable findings include:
- Vitamin D — women replete in vitamin D had significantly higher live birth rates after assisted reproductive treatment (Chu et al., 2018, Human Reproduction).
- CoQ10 — pretreatment improved ovarian response, oocyte and embryo quality in low-prognosis women undergoing IVF (Xu et al., 2018).
- Folate, B12 — long-established roles in cell division, DNA synthesis, and maternal tissue growth during pregnancy.
When to start
Most fertility practitioners recommend starting preconception nutrition at least 90 days before egg retrieval. This gives the developing egg cells the full 90-day window to benefit from optimised nutrition.
Fertility Advance and IVF
Fertility Advance is designed for the preconception window — including for women preparing for IVF. The 300mg CoQ10 dose, 800µg 5-MTHF folate, two B12 forms, and broader nutrient base are aligned with what the published research highlights.
If you're undergoing IVF, please share your supplement plan with your clinic so they can confirm it's compatible with your protocol.